Isaac Dice Room: Is This The Hardest Room In The Game?

The screen will shake and the room's effect will resolve. What does 6 dice room do? Be very careful in challenges where your character is blindfolded. You could end up completely unable to harm anything. What does a 1 room do in isaac.

1) the 2x2 room with only a small corridor around the 4 walls, with moving spike blocks all around. Getting past each of. 18 votes, 12 comments. 333k subscribers in the bindingofisaac community. Dice rooms are special rooms that can randomize many elements of the run. Dice rooms require two keys to be opened, unlike most other special rooms. For a dice room to spawn, two things must happen; First, the game must decide that a sacrifice room will spawn that floor. If i'm checking dice rooms, i'm pretty much exclusively looking for a 5 room. 5 is always helpful unless you're trying to play fast (in which case you're probably not checking dice rooms), vs all the others being either highly situational or just straight up bad. I'm curious what the hardest room someone's encountered is regardless of what items the player has. I bring this up because i was just in the cathedral and went up against 4 pride (or was it even more?) in the same room.

I'm curious what the hardest room someone's encountered is regardless of what items the player has. I bring this up because i was just in the cathedral and went up against 4 pride (or was it even more?) in the same room.